Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

Parkinson’s disease (PD) is the most common progressive neurodegenerative movement disorder, characterized by the selective loss of nigrostriatal dopaminergic neurons, and the presence of intracellular insoluble proteinaceous inclusions, known as Lewy Bodies. Although PD etiopathogenesis remai...

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Autors principals:	Diogo Martins Branco, Daniela M Arduino, A. Raquel Esteves, Diana F F Silva, Sandra M Cardoso, Catarina Oliveira
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2010-05-01
Col·lecció:	Frontiers in Aging Neuroscience
Matèries:	alpha-Synuclein Dopamine Mitochondria Proteasome Parkinson’s disease substantia nigra pars compacta
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00017/full
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