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The Role of Lipids in the Initiation of α-Synuclein Misfolding

The aggregation of α-synuclein (α-syn) is inseparably connected to Parkinson’s disease (PD). It is now well-established that certain forms of α-syn aggregates, oligomers and fibrils, can exert neurotoxicity in synucleinopathies. With the exception of rare familial forms, the vast majority of PD case...

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Principais autores: Martin Kiechle, Veselin Grozdanov, Karin M. Danzer
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020-09-01
叢編:Frontiers in Cell and Developmental Biology
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在線閱讀:https://www.frontiersin.org/article/10.3389/fcell.2020.562241/full
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