Activin-A Induces Fewer, but Larger Osteoclasts From Monocytes in Both Healthy Controls and Fibrodysplasia Ossificans Progressiva Patients

Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disease characterized by heterotopic ossification (HO) that occurs in muscle tissue, tendons, and ligaments. The disease is caused by mutations in the Activin receptor type I (ACVR1) gene resulting in enhanced responsiveness to Activin-A....

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Egile Nagusiak:	Ton Schoenmaker, Esmée Botman, Merve Sariyildiz, Dimitra Micha, Coen Netelenbos, Nathalie Bravenboer, Angele Kelder, E. Marelise W. Eekhoff, Teun J. De Vries
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2020-07-01
Saila:	Frontiers in Endocrinology
Gaiak:	fibrodysplasia ossificans progressiva Activin-A ACVR1 CD14+ monocyte osteoclast
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fendo.2020.00501/full
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