IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
Immune checkpoint blockade (ICB) therapy is a central pillar of melanoma treatment leading to durable response rates. Important mechanisms of action of ICB therapy include disinhibition of CD4<sup>+</sup> and CD8<sup>+</sup> T cells. Stimulated CD4<sup>+</sup> T helper 1 cells secrete the effector c...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
MDPI AG
2022-04-01
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| श्रृंखला: | Cells |
| विषय: | |
| ऑनलाइन पहुंच: | https://www.mdpi.com/2073-4409/11/9/1514 |
| टैग: |
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