Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies

Recently, thioxanthone derivatives were found to protect cells against toxic P-glycoprotein (P-gp) substrates, acting as potent inducers/activators of this efflux pump. The study of new P-gp chiral modulators produced from thioxanthone derivatives could clarify the enantioselectivity of this ABC tra...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Ana Lopes, Eva Martins, Renata Silva, Madalena M. M. Pinto, Fernando Remião, Emília Sousa, Carla Fernandes
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2018-03-01
Edice:	Molecules
Témata:	P-glycoprotein thioxanthones enantioselectivity expression activation
On-line přístup:	http://www.mdpi.com/1420-3049/23/3/626
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!