Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies
Recently, thioxanthone derivatives were found to protect cells against toxic P-glycoprotein (P-gp) substrates, acting as potent inducers/activators of this efflux pump. The study of new P-gp chiral modulators produced from thioxanthone derivatives could clarify the enantioselectivity of this ABC tra...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2018-03-01
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| Серии: | Molecules |
| Предметы: | |
| Online-ссылка: | http://www.mdpi.com/1420-3049/23/3/626 |
| Метки: |
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