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Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells

(1) Background: Our previous studies unveiled the hit thioxanthone TXA1 as an inhibitor of P-glycoprotein (drug efflux pump) and of human tumor cells growth, namely of melanoma cells. Since TXA1 is structurally similar to lucanthone (an autophagy inhibitor and apoptosis inducer) and to N10-substitut...

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Autori principali: Raquel T. Lima, Diana Sousa, Ana M. Paiva, Andreia Palmeira, João Barbosa, Madalena Pedro, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2016-10-01
Serie:Molecules
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Accesso online:http://www.mdpi.com/1420-3049/21/10/1343
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