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Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological processes: oxygen transport and storage, electron transfer, drug and steroid metabolism, signal transduction, and micro RNA processing. However, excess free-heme is highly toxic due to its ability to promote oxid...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Deborah eChiabrando, Francesca eVinchi, Veronica eFiorito, Sonia eMercurio, Emanuela eTolosano
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2014-04-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00061/full
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