Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological processes: oxygen transport and storage, electron transfer, drug and steroid metabolism, signal transduction, and micro RNA processing. However, excess free-heme is highly toxic due to its ability to promote oxid...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Deborah eChiabrando, Francesca eVinchi, Veronica eFiorito, Sonia eMercurio, Emanuela eTolosano
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2014-04-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	Hemopexin ABCG2 HO-1 FLVCR1 FLVCR2 HCP1/PCFT
Онлайн хандалт:	http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00061/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!