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Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological processes: oxygen transport and storage, electron transfer, drug and steroid metabolism, signal transduction, and micro RNA processing. However, excess free-heme is highly toxic due to its ability to promote oxid...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Deborah eChiabrando, Francesca eVinchi, Veronica eFiorito, Sonia eMercurio, Emanuela eTolosano
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2014-04-01
Σειρά:Frontiers in Pharmacology
Θέματα:
Διαθέσιμο Online:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00061/full
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