EZH2 negatively regulates IL‐8 expression in human nasal epithelial cells through its histone methyltransferase activity

Abstract Background Chronic rhinosinusitis (CRS), characterized by persistent inflammation of the nasal and sinus mucosa, exhibits an escalating global prevalence and incidence. Interleukin‐8 (IL‐8), a key chemokine driving neutrophil recruitment, is implicated in CRS pathogenesis. While non‐epigene...

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Detalhes bibliográficos

Principais autores:	Yu Song, Minghang Yu, Yuan Zhang, Xi Wang, Xiangyi Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-09-01
coleção:	Eye & ENT Research
Assuntos:	chronic rhinosinusitis enhancer of zeste homolog 2 epigenetics histone methylation interleukin‐8
Acesso em linha:	https://doi.org/10.1002/eer3.70020
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