Epigenetic age acceleration and risk of aortic valve stenosis: a bidirectional Mendelian randomization study

Abstract Background Aortic valve stenosis (AVS) is the most prevalent cardiac valve lesion in developed countries, and pathogenesis is closely related to aging. DNA methylation-based epigenetic clock is now recognized as highly accurate predictor of the aging process and associated health outcomes....

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מידע ביבליוגרפי

Principais autores:	Wanqian Pan, Qi Huang, Le Zhou, Jia Lin, Xiaojiao Du, Xiaodong Qian, Tingbo Jiang, Weixiang Chen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-03-01
סדרה:	Clinical Epigenetics
נושאים:	Aortic valve stenosis Bidirectional Mendelian randomization Biological aging Epigenetic clock Genome-wide association study
גישה מקוונת:	https://doi.org/10.1186/s13148-024-01647-5
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