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Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early <it>Xenopus </it>embryos

<p>Abstract</p> <p>Background</p> <p>DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation can be bound by methyl-CpG-binding domain proteins (MBDs) and specific zinc finger proteins, which can recruit co-repressor complexes to silence transc...

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Autors principals: Bogdanović Ozren, Veenstra Gert Jan C
Format: Artigo
Idioma:Inglês
Publicat: BMC 2011-08-01
Col·lecció:BMC Research Notes
Accés en línia:http://www.biomedcentral.com/1756-0500/4/300
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