Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early <it>Xenopus </it>embryos
<p>Abstract</p> <p>Background</p> <p>DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation can be bound by methyl-CpG-binding domain proteins (MBDs) and specific zinc finger proteins, which can recruit co-repressor complexes to silence transc...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2011-08-01
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| Edice: | BMC Research Notes |
| On-line přístup: | http://www.biomedcentral.com/1756-0500/4/300 |
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