Near Miss or Standard of Care? <i>DPYD</i> Screening for Cancer Patients Receiving Fluorouracil
5-fluorouracil (5-FU) and its pro-drug capecitabine are widely used anticancer agents. Most 5-FU catabolism is dependent on dihydropyrimidine dehydrogenase (DPD) encoded by the <i>DPYD</i> gene, and <i>DPYD</i> variants that reduce DPD function increase 5-FU toxicity. Most DPD deficient patients are...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2020-12-01
|
| Серии: | Current Oncology |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/1718-7729/28/1/12 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|