Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

Glutamatergic receptor expression is mostly unknown in adults with fragile X syndrome (FXS). Favorable behavioral effects of negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR₅) in <i>fmr1</i> knockout (KO) mouse models have not been confirmed in...

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Bibliografische gegevens

Hoofdauteurs:	James R. Brašić, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Anil Mathur, Keith Slifer, Thomas Sedlak, Samuel D. Martin, Zabecca Brinson, Pankhuri Vyas, John P. Seibyl, Elizabeth M. Berry-Kravis, Dean F. Wong, Dejan B. Budimirovic
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2020-11-01
Reeks:	Brain Sciences
Onderwerpen:	binding potential caudate nucleus <i>FMR1</i> gene Fragile X Mental Retardation Protein (FMRP) genetic mutation magnetic resonance imaging (MRI)
Online toegang:	https://www.mdpi.com/2076-3425/10/12/899
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