Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

Glutamatergic receptor expression is mostly unknown in adults with fragile X syndrome (FXS). Favorable behavioral effects of negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR₅) in <i>fmr1</i> knockout (KO) mouse models have not been confirmed in...

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Detalles Bibliográficos

Principais autores:	James R. Brašić, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Anil Mathur, Keith Slifer, Thomas Sedlak, Samuel D. Martin, Zabecca Brinson, Pankhuri Vyas, John P. Seibyl, Elizabeth M. Berry-Kravis, Dean F. Wong, Dejan B. Budimirovic
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-11-01
Series:	Brain Sciences
Assuntos:	binding potential caudate nucleus <i>FMR1</i> gene Fragile X Mental Retardation Protein (FMRP) genetic mutation magnetic resonance imaging (MRI)
Acceso en liña:	https://www.mdpi.com/2076-3425/10/12/899
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