DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy
α-Synuclein misfolding and aggregation play an important role in the pathogenesis of Parkinson’s disease (PD). Loss of function and mutation of the PARK7/DJ-1 gene cause early-onset familial PD. DJ-1 can inhibit α-synuclein aggregation, and may function at an early step in the aggregation process. S...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Frontiers Media S.A.
2017-09-01
|
| Rangatū: | Frontiers in Aging Neuroscience |
| Ngā marau: | |
| Urunga tuihono: | http://journal.frontiersin.org/article/10.3389/fnagi.2017.00308/full |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|