RETRACTED ARTICLE: Hurdles to breakthrough in CAR T cell therapy of solid tumors

Abstract Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have shown promising outcomes and emerged as a new curative option for hematological malignancy, especially malignant neoplasm of B cells. Notably, when T cells are transduced with CAR constructs, composed...

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Hlavní autoři:	Faroogh Marofi, Harun Achmad, Dmitry Bokov, Walid Kamal Abdelbasset, Zeid Alsadoon, Supat Chupradit, Wanich Suksatan, Siavash Shariatzadeh, Zahra Hasanpoor, Mahboubeh Yazdanifar, Navid Shomali, Farhad Motavalli Khiavi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2022-04-01
Edice:	Stem Cell Research & Therapy
Témata:	Chimeric antigen receptor CAR-T cell Solid tumors Tumor microenvironment
On-line přístup:	https://doi.org/10.1186/s13287-022-02819-x
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!