RETRACTED ARTICLE: Hurdles to breakthrough in CAR T cell therapy of solid tumors

Abstract Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have shown promising outcomes and emerged as a new curative option for hematological malignancy, especially malignant neoplasm of B cells. Notably, when T cells are transduced with CAR constructs, composed...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Faroogh Marofi, Harun Achmad, Dmitry Bokov, Walid Kamal Abdelbasset, Zeid Alsadoon, Supat Chupradit, Wanich Suksatan, Siavash Shariatzadeh, Zahra Hasanpoor, Mahboubeh Yazdanifar, Navid Shomali, Farhad Motavalli Khiavi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2022-04-01
Цуврал:	Stem Cell Research & Therapy
Нөхцлүүд:	Chimeric antigen receptor CAR-T cell Solid tumors Tumor microenvironment
Онлайн хандалт:	https://doi.org/10.1186/s13287-022-02819-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!