The <i>Trypanosoma brucei</i>-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells

The extracellular parasite and causative agent of African sleeping sickness <i>Trypanosoma brucei</i> (<i>T. brucei</i>) has evolved a number of strategies to avoid immune detection in the host. One recently described mechanism involves the conversion of host-derived amino acids to aromatic ketoacid...

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Auteurs principaux:	Hannah K. Fitzgerald, Sinead A. O’Rourke, Eva Desmond, Nuno G. B. Neto, Michael G. Monaghan, Miriam Tosetto, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Derek P. Nolan, Jean M. Fletcher, Aisling Dunne
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2022-01-01
Collection:	Antioxidants
Sujets:	heme oxygenase 1 <i>Trypanosoma brucei</i> inflammatory bowel disease aromatic ketoacids dendritic cells immunomodulation
Accès en ligne:	https://www.mdpi.com/2076-3921/11/1/164
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