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Interplay between ubiquitin, SUMO and poly(ADP-ribose) in the cellular response to genotoxic stress

Cells employ a complex network of molecular pathways to cope with endogenous and exogenous genotoxic stress. This multilayered response ensures that genomic lesions are efficiently detected and faithfully repaired in order to safeguard genome integrity. The molecular choreography at sites of DNA dam...

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Autores principales: Stefania ePellegrino, Matthias eAltmeyer
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016-04-01
Colección:Frontiers in Genetics
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Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00063/full
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