Human Host Defense Peptide LL-37 Suppresses TNFα-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells

Introduction: TNFα-inducible matrix metalloproteinases play a critical role in the process of airway remodeling in respiratory inflammatory disease including asthma. The cationic host defense peptide LL-37 is elevated in the lungs during airway inflammation. However, the impact of LL-37 on TNFα-driv...

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Үндсэн зохиолчид:	Anthony Altieri, Courtney Lynn Marshall, Padmanie Ramotar, Dylan Lloyd, Mahadevappa Hemshekhar, Victor Spicer, Anne M. van der Does, Neeloffer Mookherjee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Karger Publishers 2024-03-01
Цуврал:	Journal of Innate Immunity
Нөхцлүүд:	cathelicidin ll-37 tnfα host defense peptides inflammation matrix metalloproteinases airway remodeling
Онлайн хандалт:	https://beta.karger.com/Article/FullText/537775
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!