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Efficacy of Cathelicidin LL-37 in an MRSA Wound Infection Mouse Model

Background: LL-37 is the only human antimicrobial peptide that belongs to the cathelicidins. The aim of the study was to evaluate the efficacy of LL-37 in the management of MRSA-infected surgical wounds in mice. Methods: A wound on the back of adult male BALB/c mice was made and inoculated with <i>S...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Oriana Simonetti, Oscar Cirioni, Gaia Goteri, Guendalina Lucarini, Elżbieta Kamysz, Wojciech Kamysz, Fiorenza Orlando, Giulio Rizzetto, Elisa Molinelli, Gianluca Morroni, Roberto Ghiselli, Mauro Provinciali, Andrea Giacometti, Annamaria Offidani
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-10-01
Schriftenreihe:Antibiotics
Schlagworte:
animal models
cathelicidin
LL-37
VEGF
wound
Online-Zugang:https://www.mdpi.com/2079-6382/10/10/1210
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