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The Cellular and Developmental Roles of Cullins, Neddylation, and the COP9 Signalosome in Dictyostelium discoideum

Cullins (CULs) are a core component of cullin-RING E3 ubiquitin ligases (CRLs), which regulate the degradation, function, and subcellular trafficking of proteins. CULs are post-translationally regulated through neddylation, a process that conjugates the ubiquitin-like modifier protein neural precurs...

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Bibliografski detalji
Glavni autori: William D. Kim, Sabateeshan Mathavarajah, Robert J. Huber
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-03-01
Serija:Frontiers in Physiology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fphys.2022.827435/full
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