The Cellular and Developmental Roles of Cullins, Neddylation, and the COP9 Signalosome in Dictyostelium discoideum
Cullins (CULs) are a core component of cullin-RING E3 ubiquitin ligases (CRLs), which regulate the degradation, function, and subcellular trafficking of proteins. CULs are post-translationally regulated through neddylation, a process that conjugates the ubiquitin-like modifier protein neural precurs...
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2022-03-01
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| Schriftenreihe: | Frontiers in Physiology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fphys.2022.827435/full |
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