The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir.

The persistence of latently infected CD4 + T-cells in people with HIV (PWH) on suppressive antiretroviral therapy (ART) is the major barrier to an HIV cure. We investigated the impact of two classes of pro-apoptotic drugs, phosphoinositide-3 kinases (PI3K) inhibitors or the B cell lymphoma 2 (Bcl-2)...

Descripción completa

Detalles Bibliográficos

Autores principales:	Youry Kim, Jenny L Anderson, Carolin Tumpach, Ajantha Solomon, Jesslyn Ong, Kiho Tanaka, Jennifer M Zerbato, Tania Tan, Charis E Teh, Daniel H D Gray, Philip Arandjelovic, James McMahon, Niamh Meagher, David Price, Marc Pellegrini, Michael Roche, Sharon R Lewin
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2026-01-01
Colección:	PLoS Pathogens
Acceso en línea:	https://doi.org/10.1371/journal.ppat.1013923
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!