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Eight Triplex-Binding Molecules from Four Chemical Classes Broadly Recognize the MALAT1 Triple Helix

RNA triple helices are relatively understudied, including their interactions with small molecules. In this study, we evaluated eight previously reported triplex-binding molecules (TBMs) for their functional effects on the premature and mature MALAT1 triple helix. Based on UV thermal denaturation exp...

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Autores principales: Madeline M. Mousseau, Krishna M. Shivakumar, Jaesang Yoo, Jessica A. Brown
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2025-11-01
Colección:Molecules
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Acceso en línea:https://www.mdpi.com/1420-3049/30/21/4277
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