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Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy

Triplex-forming oligonucleotides (TFOs) can bind to the major groove of double-stranded DNA with high specificity and affinity and inhibit gene expression. Triplex-forming oligonucleotides have gained prominence because of their potential applications in antigene therapy. In particular, the target s...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chun Li, Zunzhen Zhou, Chao Ren, Yi Deng, Feng Peng, Qiongfen Wang, Hong Zhang, Yuan Jiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2022-12-01
Sarja:Frontiers in Pharmacology
Aiheet:
Linkit:https://www.frontiersin.org/articles/10.3389/fphar.2022.1007723/full
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