A Series of Novel 1-<i>H</i>-isoindole-1,3(2<i>H</i>)-dione Derivatives as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: In Silico, Synthesis and In Vitro Studies

The derivatives of isoindoline-1,3-dione are interesting due to their biological activities, such as anti-inflammatory and antibacterial effects. Several series have been designed and evaluated for Alzheimer’s therapy candidates. They showed promising activity. In this work, six new derivatives were...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Edward Krzyżak, Aleksandra Marciniak, Dominika Szkatuła, Klaudia A. Jankowska, Natalia Dobies, Aleksandra Kotynia
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2024-07-01
Sarja:	Molecules
Aiheet:	isoindoline-1,3-dione neurodegenerative diseases acetylcholinesterase butyrylcholinesterase synthesis of phthalimide derivatives molecular docking and dynamics
Linkit:	https://www.mdpi.com/1420-3049/29/15/3528
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