Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages

Abstract The Retinoblastoma (Rb) family of pocket proteins (p107, Rb, and p130) controls all aspects of neurogenesis from stem cell activation to long-term neuronal survival in the brain. Previous studies have reported non-overlapping, often complementary, roles for these cell cycle regulators with...

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Hlavní autoři:	Reem Swaidan, Ahmad Daher, Anthony T. Bejjani, Yara E. El Atie, Yasmina Chehab, Razan Bou Hamdan, Renaud Vandenbosch, Ruth S. Slack, Saad Omais, Noël Ghanem
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2025-07-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-025-07815-6
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