Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages

Abstract The Retinoblastoma (Rb) family of pocket proteins (p107, Rb, and p130) controls all aspects of neurogenesis from stem cell activation to long-term neuronal survival in the brain. Previous studies have reported non-overlapping, often complementary, roles for these cell cycle regulators with...

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Главные авторы:	Reem Swaidan, Ahmad Daher, Anthony T. Bejjani, Yara E. El Atie, Yasmina Chehab, Razan Bou Hamdan, Renaud Vandenbosch, Ruth S. Slack, Saad Omais, Noël Ghanem
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2025-07-01
Серии:	Cell Death and Disease
Online-ссылка:	https://doi.org/10.1038/s41419-025-07815-6
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