The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis

Clinical success of Toll-Like receptor-4 (TLR-4) antagonists in sepsis therapy has thus far been lacking. As inhibition of a receptor can only be useful if the receptor is active, stratification of patients with active TLR-4 would be desirable. Our aim was to establish an assay to quantify phosphory...

Descripció completa

Dades bibliogràfiques

Autors principals:	Patrick Thon, Katharina Rump, Annika Knorr, Birte Dyck, Dominik Ziehe, Matthias Unterberg, Hartmuth Nowak, Lars Bergmann, Alexander Wolf, Maha Bazzi, Jennifer Orlowski, Marcus Peters, Alexander Zarbock, Thorsten Brenner, Michael Adamzik, Tim Rahmel, Björn Koos
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-09-01
Col·lecció:	Cells
Matèries:	sepsis Toll-Like Receptor 4 proximity ligation assay
Accés en línia:	https://www.mdpi.com/2073-4409/11/19/3020
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!