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AIMing for survival: The impact of the free and total AIM concentration in septic patients

BackgroundSepsis, a life-threatening condition caused by a dysregulated host response to infection, remains a major cause of mortality worldwide. Identifying reliable biomarkers for prognosis and treatment is urgently needed. This study investigates the role of the Apoptosis Inhibitor of Macrophages...

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Principais autores: Birte Dyck, Ulrich Bosch dos Santos, Corinna Müller, Hartmuth Nowak, Tim Rahmel, Lars Palmowski, Matthias Unterberg, Alexander Wolf, Alexander von Busch, Andrea Witowski, Britta Westhus, Barbara Sitek, Katharina Rump, Christian Putensen, Stefan Felix Ehrentraut, Alexander Zarbock, Dietrich Henzler, Nina Babel, Martin Eisenacher, Katrin Marcus, Björn Ellger, Björn Koos, Michael Adamzik, Dominik Ziehe, Lars Bergmann
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Immunology
Fag:
apoptosis inhibitor of macrophages (AIM)
CD5L
SepsisDataNet.NRW
IgM
Pentaglobin®
sepsis
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1685119/full
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