Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
Acidic tissue microenvironment contributes to tumor progression via multiple effects including the activation of angiogenic factors and proteases, reduced cell-cell adhesion, increased migration and invasion, etc. In addition, intratumoral acidosis can influence the uptake of anticancer drugs and mo...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2014-01-01
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| シリーズ: | Frontiers in Physiology |
| 主題: | |
| オンライン･アクセス: | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00400/full |
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