Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors

Acidic tissue microenvironment contributes to tumor progression via multiple effects including the activation of angiogenic factors and proteases, reduced cell-cell adhesion, increased migration and invasion, etc. In addition, intratumoral acidosis can influence the uptake of anticancer drugs and mo...

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Bibliografski detalji

Glavni autori:	Olga eSedlakova, Eliska eSvastova, Martina eTakacova, Juraj eKopacek, Jaromir ePastorek, Silvia ePastorekova
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2014-01-01
Serija:	Frontiers in Physiology
Teme:	Acidosis Metabolism Survival Tumor Microenvironment metastasis hypoxia
Online pristup:	http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00400/full
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