A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model

Nanosized drug delivery systems targeting transporters of the blood-brain barrier (BBB) are promising carriers to enhance the penetration of therapeutics into the brain. The expression of solute carriers (SLC) is high and shows a specific pattern at the BBB. Here we show that targeting ligands ascor...

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Detalhes bibliográficos

Principais autores:	Szilvia Veszelka, Mária Mészáros, Gergő Porkoláb, Anikó Szecskó, Nóra Kondor, Györgyi Ferenc, Tamás F. Polgár, Gábor Katona, Zoltán Kóta, Lóránd Kelemen, Tibor Páli, Judit P. Vigh, Fruzsina R. Walter, Silvia Bolognin, Jens C. Schwamborn, Jeng-Shiung Jan, Mária A. Deli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-12-01
coleção:	Pharmaceutics
Assuntos:	blood-brain barrier brain endothelial cell drug targeting nanoparticle triple targeting ligand solute carrier
Acesso em linha:	https://www.mdpi.com/1999-4923/14/1/86
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