PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier

Abstract Background Nanocarriers targeting the blood-brain barrier (BBB) are promising drug delivery systems to enhance the penetration of therapeutic molecules into the brain. Immunotherapy, particularly monoclonal antibodies designed to bind amyloid-beta peptides have become a promising strategy f...

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Главные авторы:	Anikó Szecskó, Mária Mészáros, Beatriz Simões, Marco Cavaco, Catarina Chaparro, Gergő Porkoláb, Miguel A.R.B. Castanho, Mária A. Deli, Vera Neves, Szilvia Veszelka
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-04-01
Серии:	Fluids and Barriers of the CNS
Предметы:	Blood-brain barrier Brain delivery Nanoparticle PepH3 Single domain antibody
Online-ссылка:	https://doi.org/10.1186/s12987-025-00641-0
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