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Preparation, characterization, and in vivo pharmacokinetics of thermosensitive in situ nasal gel of donepezil hydrochloride

Donepezil hydrochloride thermosensitive in situ gel for nasal delivery was prepared by using Poloxamer 407 and Poloxamer 188 as thermoreversible polymers, hydroxypropyl-β-cyclodextrin and ethylparaben as permeation enhancer and preservative, respectively. The gelation temperature and time, pH value...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gu Fugen, Fan Huimin, Cong Zhixin, Li Shuang, Wang Yi, Wu Chunzhi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Sciendo 2020-09-01
Saila:Acta Pharmaceutica
Gaiak:
Sarrera elektronikoa:https://doi.org/10.2478/acph-2020-0032
Etiketak: Etiketa erantsi
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