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RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression

Abstract Background Human telomerase reverse transcriptase (hTERT) is highly expressed in over 80% of tumors, including human epithelial ovarian cancer (EOC). However, the mechanisms through which hTERT is up-regulated in EOC and promotes tumor progression remain unclear. The aim of this study is to...

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Principais autores: Yong-Bin Liu, Ying Mei, Jing Long, Yu Zhang, Dong-Li Hu, Hong-Hao Zhou
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-08-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Ovarian cancer
RIF1
Telomerase reverse transcriptase
hTERT
Online adgang:http://link.springer.com/article/10.1186/s13046-018-0854-8
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