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Diverse regulatory manners of human telomerase reverse transcriptase

Abstract Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer cell stemness maintaining, cell proliferation, apoptosis inhibition, senescence ev...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Meng-Meng Jie, Xing Chang, Shuo Zeng, Cheng Liu, Guo-Bin Liao, Ya-Ran Wu, Chun-Hua Liu, Chang-Jiang Hu, Shi-Ming Yang, Xin-Zhe Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-06-01
Schriftenreihe:Cell Communication and Signaling
Schlagworte:
hTERT
Regulation
Transcription
Post-transcription
Post-translational modification
Online-Zugang:http://link.springer.com/article/10.1186/s12964-019-0372-0
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