Gonadal androgens are associated with decreased type I interferon production by plasmacytoid dendritic cells and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents

mRNA vaccine technologies introduced following the SARS-CoV-2 pandemic have highlighted the need to better understand the interaction of adjuvants and the early innate immune response. Type I interferon (IFN-I) is an integral part of this early innate response that primes several components of the a...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Oliver L. Sampson, Cecilia Jay, Emily Adland, Anna Csala, Nicholas Lim, Stella M. Ebbrecht, Lorna C. Gilligan, Angela E. Taylor, Sherley Sherafin George, Stephanie Longet, Lucy C. Jones, Ellie Barnes, John Frater, Paul Klenerman, Susie Dunachie, Miles Carrol, James Hawley, Wiebke Arlt, Andreas Groll, Philip Goulder
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-02-01
Sarja:	Frontiers in Immunology
Aiheet:	type I interferon plasmacytoid dendritic cell immune sex difference androgen adolescent vaccination
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1329805/full
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