mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals

Two doses of BNT162b2 mRNA vaccine induces a strong systemic SARS-CoV-2 specific humoral response. However, SARS-CoV-2 airborne transmission makes mucosal immune response a crucial first line of defense. Therefore, we characterized SARS-CoV-2-specific IgG responses induced by BNT162b2 vaccine, as we...

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Bibliografski detalji

Glavni autori:	Stephanie Longet, Alexander Hargreaves, Saoirse Healy, Rebecca Brown, Hailey R. Hornsby, Naomi Meardon, Tom Tipton, Eleanor Barnes, Susanna Dunachie, Christopher J. A. Duncan, Paul Klenerman, Alex Richter, Lance Turtle, Thushan I. de Silva, Miles W. Carroll
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-09-01
Serija:	Frontiers in Immunology
Teme:	antibody responses mucosal immunity SARS-CoV-2 mRNA vaccination neutralizing responses ACE2 inhibition
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.953949/full
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