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Complement-mediated enhancement of SARS-CoV-2 antibody neutralisation potency in vaccinated individuals

Abstract With the continued emergence of SARS-CoV-2 variants and concerns of waning immunity, there is a need for better defined correlates of protection to aid future vaccine and therapeutic developments. Whilst neutralising antibody titres are associated with protection, these are typically determ...

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Autori principali: Jack Mellors, Raman Dhaliwal, Stephanie Longet, Tom Tipton, OCTAVE Consortium, OPTIC Consortium, Eleanor Barnes, Susanna J. Dunachie, Paul Klenerman, Julian Hiscox, Miles Carroll
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-03-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-025-57947-8
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