Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

Tendon repair remains challenging due to its poor intrinsic healing capacity, and stem cell therapy has emerged as a promising strategy to promote tendon regeneration. Nevertheless, the inflammatory environment following acute tendon injuries disrupts stem cell differentiation, leading to unsatisfie...

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Príomhchruthaitheoirí:	Jialin Chen, Renwang Sheng, Qingyun Mo, Ludvig J. Backman, Zhiyuan Lu, Qiuzi Long, Zhixuan Chen, Zhicheng Cao, Yanan Zhang, Chuanquan Liu, Haotian Zheng, Yu Qi, Mumin Cao, Yunfeng Rui, Wei Zhang
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	KeAi Communications Co., Ltd. 2025-02-01
Sraith:	Bioactive Materials
Ábhair:	Acute tendon injury Stem cell therapy NF-κB signaling Tenogenic differentiation Multiomics
Rochtain ar líne:	http://www.sciencedirect.com/science/article/pii/S2452199X24004614
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!

Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

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