Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

Tendon repair remains challenging due to its poor intrinsic healing capacity, and stem cell therapy has emerged as a promising strategy to promote tendon regeneration. Nevertheless, the inflammatory environment following acute tendon injuries disrupts stem cell differentiation, leading to unsatisfie...

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Hlavní autoři:	Jialin Chen, Renwang Sheng, Qingyun Mo, Ludvig J. Backman, Zhiyuan Lu, Qiuzi Long, Zhixuan Chen, Zhicheng Cao, Yanan Zhang, Chuanquan Liu, Haotian Zheng, Yu Qi, Mumin Cao, Yunfeng Rui, Wei Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	KeAi Communications Co., Ltd. 2025-02-01
Edice:	Bioactive Materials
Témata:	Acute tendon injury Stem cell therapy NF-κB signaling Tenogenic differentiation Multiomics
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2452199X24004614
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