Polyphenol-Rich Extracts from <i>Annurca</i> Apple Differentially Modulate Oxidative Stress-Induced Senescence in Human Dermal Fibroblasts

Cellular senescence of dermal fibroblasts is a central mechanism underlying skin aging and is closely linked to oxidative imbalance and mitochondrial dysfunction. In this study, we investigated the senotherapeutic effects of polyphenol-rich extracts obtained from peel and flesh of <i>Malus pumila</i...

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Auteurs principaux:	Claudia Moriello, Nicola Alessio, Pasquale Perrone, Tiziana Squillaro, Stefania D’Angelo, Umberto Galderisi, Giovanni Di Bernardo
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2026-03-01
Collection:	Antioxidants
Sujets:	senescence human dermal fibroblast polyphenols <i>Annurca</i> apple oxidative stress mitochondrial dysfunction
Accès en ligne:	https://www.mdpi.com/2076-3921/15/3/372
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