Polyphenol-Rich Extracts from <i>Annurca</i> Apple Differentially Modulate Oxidative Stress-Induced Senescence in Human Dermal Fibroblasts

Cellular senescence of dermal fibroblasts is a central mechanism underlying skin aging and is closely linked to oxidative imbalance and mitochondrial dysfunction. In this study, we investigated the senotherapeutic effects of polyphenol-rich extracts obtained from peel and flesh of <i>Malus pumila</i...

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Hlavní autoři:	Claudia Moriello, Nicola Alessio, Pasquale Perrone, Tiziana Squillaro, Stefania D’Angelo, Umberto Galderisi, Giovanni Di Bernardo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2026-03-01
Edice:	Antioxidants
Témata:	senescence human dermal fibroblast polyphenols <i>Annurca</i> apple oxidative stress mitochondrial dysfunction
On-line přístup:	https://www.mdpi.com/2076-3921/15/3/372
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