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Small Molecule Antibiotics Inhibit Distinct Stages of Bacterial Outer Membrane Protein Assembly

ABSTRACT Several antibacterial compounds have recently been discovered that potentially inhibit the activity of BamA, an essential subunit of a heterooligomer (the barrel assembly machinery or BAM) that assembles outer membrane proteins (OMPs) in Gram-negative bacteria, but their mode of action is u...

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Detaylı Bibliyografya
Asıl Yazarlar: Janine H. Peterson, Matthew Thomas Doyle, Harris D. Bernstein
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2022-10-01
Seri Bilgileri:mBio
Konular:
Online Erişim:https://journals.asm.org/doi/10.1128/mbio.02286-22
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