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The Role of HDACs as Leukemia Therapy Targets using HDI

Histone deacetylases (HDACs) are the enzymes causing deacetylation of histone and non-histone substrates. Histone deacetylase inhibitors (HDIs) are a family of drugs eliminating the effect of HDACs in malignant cells via inhibition of HDACs. Due to extensive effects upon gene expression through inte...

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Autors principals: Ahmad Ahmadzadeh, Elahe Khodadi, Mohammad Shahjahani, Jessika Bertacchini, Tina Vosoughi, Najmaldin Saki
Format: Artigo
Idioma:Inglês
Publicat: Tehran University of Medical Sciences 2016-02-01
Col·lecció:International Journal of Hematology-Oncology and Stem Cell Research
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Accés en línia:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/367
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